Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380211 | 0.87 | PTK2 (0.51) | PTK2IGF1REGFRNUAK2NUAK1 | |
| SCHEMBL28531524 | 0.87 | PTK2 (0.51) | PTK2IGF1REGFRNUAK2NUAK1 | |
| SCHEMBL28546133 | 0.87 | SLC2A1 (0.49) | SLC2A1PTK2JAK3IGF1RCSF1R | |
| SCHEMBL30380226 | 0.87 | SLC2A1 (0.49) | SLC2A1PTK2JAK3IGF1RCSF1R | |
| SCHEMBL21596338 | 0.84 | FGFR4 (0.51) | PTK2JAK3FGFR1JAK2FLT3 | |
| SCHEMBL30379391 | 0.84 | LRRK2 (0.49) | SLC2A1PTK2JAK3IGF1RCSF1R | |
| Trifluoroacetic Acid SCHEMBL21596381 | 0.83 | PTK2 (0.47) | PTK2IGF1REGFRPLK1PLK3 | |
| SCHEMBL28525616 | 0.82 | WEE1 (0.57) | SLC2A1PTK2JAK3IGF1RCSF1R | |
| SCHEMBL21600825 | 0.82 | EGFR (0.44) | PTK2JAK3IGF1RCSF1RFGFR1 | |
| SCHEMBL28546957 | 0.82 | SLC2A1 (0.43) | SLC2A1PTK2JAK3IGF1RCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |