Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 17/20 | 0.46 |
| ▸ | NUAK2 | Q9H093 | 2/20 | 0.46 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531524 | 1.00 | PTK2 (0.51) | PTK2EGFRNUAK2NUAK1IGF1R | |
| Trifluoroacetic Acid SCHEMBL21596381 | 0.96 | PTK2 (0.47) | PTK2EGFRNUAK2NUAK1IGF1R | |
| SCHEMBL30379302 | 0.87 | SLC2A1 (0.47) | PTK2EGFRNUAK2NUAK1IGF1R | |
| SCHEMBL21596338 | 0.84 | FGFR4 (0.51) | PTK2EGFRNUAK2NUAK1 | |
| SCHEMBL28532459 | 0.83 | FGFR1 (0.49) | PTK2EGFRIGF1RCDK2 | |
| SCHEMBL30379611 | 0.83 | FGFR1 (0.49) | PTK2EGFRIGF1RCDK2 | |
| SCHEMBL21600825 | 0.83 | EGFR (0.44) | PTK2EGFRNUAK2NUAK1IGF1R | |
| SCHEMBL28533769 | 0.82 | ALK (0.56) | PTK2EGFRIGF1R | |
| SCHEMBL28953571 | 0.82 | ALK (0.58) | PTK2EGFRNUAK1IGF1R | |
| SCHEMBL28909338 | 0.81 | ALK (0.55) | PTK2EGFRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |