SCHEMBL30379656

SCHEMBL30379656

N#C/C(=C\c1cccc(C(F)(F)F)c1Cl)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KDM4E B2RXH2 3/20 0.48
PKM P14618 1/20 0.48
KMT2A Q03164 1/20 0.48
EGFR P00533 3/20 0.43
CISD1 Q9NZ45 1/20 0.41
SLC16A3 O15427 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
SLC16A1 P53985 1/20 0.41
GPR35 Q9HC97 1/20 0.41
CTSS P25774 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20603125 1.00 LMNA (0.48) LMNASMN1; SMN2KDM4EPKMKMT2A
SCHEMBL4661444 0.85 LMNA (0.61) LMNASMN1; SMN2KDM4EPKMKMT2A
SCHEMBL4661446 0.85 LMNA (0.61) LMNASMN1; SMN2KDM4EPKMKMT2A
SCHEMBL8478479 0.82 ALDH1A1 (0.47) LMNASMN1; SMN2KDM4EPKMKMT2A
SCHEMBL9458765 0.81 MAPT (0.53) LMNASMN1; SMN2KDM4EKMT2AALDH1A1
SCHEMBL9458769 0.81 MAPT (0.53) LMNASMN1; SMN2KDM4EKMT2AALDH1A1
SCHEMBL10794927 0.81 KDM4E (0.54) LMNAKDM4EPKMKMT2AEGFR
SCHEMBL10794933 0.81 KDM4E (0.54) LMNAKDM4EPKMKMT2AEGFR
SCHEMBL3028841 0.81 LMNA (0.49) LMNASMN1; SMN2KDM4EEGFRCISD1
SCHEMBL3028840 0.81 LMNA (0.49) LMNASMN1; SMN2KDM4EEGFRCISD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036586-A Compositions and methods for modulating hair growth 加利福尼亚大学董事会 2026-05-15 CN disclosed
CN-116120314-A Compositions and methods for modulating hair growth 加利福尼亚大学董事会 2023-05-16 CN disclosed