Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.46 |
| ▸ | CD38 | P28907 | 5/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338601 | 0.86 | P2RX7 (0.51) | TNKSP2RX7CD38ACKR3 | |
| SCHEMBL7019900 | 0.82 | CD38 (0.57) | TNKSP2RX7CD38ACKR3 | |
| SCHEMBL25053100 | 0.82 | GRM5 (0.63) | SSTR4SMYD3 | |
| SCHEMBL30363652 | 0.81 | P2RX7 (0.53) | TNKSP2RX7CD38SMYD3ACKR3 | |
| SCHEMBL30380003 | 0.81 | CD38 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SSTR4 | |
| SCHEMBL19132865 | 0.81 | CD38 (0.61) | TNKSP2RX7CD38SMYD3ACKR3 | |
| SCHEMBL5308759 | 0.80 | P2RX7 (0.51) | TNKSP2RX7CD38SMYD3ACKR3 | |
| SCHEMBL25417634 | 0.80 | SMYD3 (0.55) | TNKSP2RX7CD38SMYD3 | |
| SCHEMBL29998657 | 0.80 | P2RX7 (0.51) | TNKSP2RX7CD38SMYD3 | |
| SCHEMBL30336165 | 0.80 | SMYD3 (0.55) | TNKSP2RX7CD38SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4167982-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |