Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760721 | 0.92 | GAA (0.67) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL15071686 | 0.91 | GAA (0.69) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL30184646 | 0.90 | GAA (0.70) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL16449002 | 0.86 | GAA (0.77) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL27951641 | 0.84 | ALDH1A1 (0.65) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL30098865 | 0.84 | ALDH1A1 (0.73) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL11756934 | 0.81 | GAA (0.73) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL9491894 | 0.81 | GAA (0.73) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL30380715 | 0.80 | GAA (0.58) | GAAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL3827918 | 0.79 | GAA (0.82) | GAAMAPTALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059583-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |