Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184646 | 0.90 | GAA (0.70) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15071686 | 0.89 | GAA (0.69) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29760721 | 0.88 | GAA (0.67) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6361446 | 0.87 | GAA (0.73) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30098865 | 0.87 | ALDH1A1 (0.73) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30380731 | 0.86 | GAA (0.72) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3827918 | 0.85 | GAA (0.82) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14569376 | 0.83 | NPC1 (0.58) | GAAMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16448999 | 0.83 | L3MBTL1 (0.73) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16448996 | 0.82 | SMN1; SMN2 (0.55) | GAAMAPTALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952150-B2 | Prostaglandin transporter inhibitors and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |