Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11893213 | 1.00 | MAPT (0.52) | MAPTCXCL12TUBB1PPARGPPARD | |
| SCHEMBL30383987 | 0.88 | PPARG (0.65) | MAPTTUBB1PPARGPPARDPPARA | |
| SCHEMBL13817902 | 0.88 | PPARG (0.65) | MAPTTUBB1PPARGPPARDPPARA | |
| SCHEMBL4471370 | 0.88 | PPARG (0.65) | MAPTTUBB1PPARGPPARDPPARA | |
| SCHEMBL30384025 | 0.88 | PPARG (0.65) | MAPTTUBB1PPARGPPARDPPARA | |
| SCHEMBL14491076 | 0.80 | MAOB (0.66) | MAPTPPARGPPARDPPARACYP1B1 | |
| SCHEMBL14523081 | 0.80 | MAOB (0.66) | MAPTPPARGPPARDPPARACYP1B1 | |
| SCHEMBL15163370 | 0.80 | PPARA (0.57) | MAPTCXCL12PPARGPPARDPPARA | |
| SCHEMBL15163369 | 0.80 | PPARA (0.57) | MAPTCXCL12PPARGPPARDPPARA | |
| SCHEMBL13869121 | 0.78 | PTGS2 (0.72) | MAPTCXCL12CYP1B1CYP1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |