SCHEMBL11893213

SCHEMBL11893213

Cc1ccc(C(=O)/C=C/c2ccc(OC(C)(C)C(=O)O)c(F)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.52
▸ CXCL12 P48061 2/20 0.52
▸ TUBB1 Q9H4B7 1/20 0.51
▸ PPARG P37231 1/20 0.51
▸ PPARD Q03181 1/20 0.51
▸ PPARA Q07869 1/20 0.51
▸ CYP1B1 Q16678 2/20 0.50
▸ CYP1A1 P04798 1/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ ABCG2 Q9UNQ0 1/20 0.49
▸ ALDH1A1 P00352 3/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ HPGD P15428 1/20 0.49
▸ CA1 P00915 1/20 0.48
▸ CA2 P00918 1/20 0.48
▸ MAOA P21397 3/20 0.48
▸ MAOB P27338 3/20 0.48
▸ POLB P06746 1/20 0.48
▸ RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383121 1.00 MAPT (0.52) MAPTCXCL12TUBB1PPARGPPARD
SCHEMBL30383987 0.88 PPARG (0.65) MAPTTUBB1PPARGPPARDPPARA
SCHEMBL13817902 0.88 PPARG (0.65) MAPTTUBB1PPARGPPARDPPARA
SCHEMBL4471370 0.88 PPARG (0.65) MAPTTUBB1PPARGPPARDPPARA
SCHEMBL30384025 0.88 PPARG (0.65) MAPTTUBB1PPARGPPARDPPARA
SCHEMBL14491076 0.80 MAOB (0.66) MAPTPPARGPPARDPPARACYP1B1
SCHEMBL14523081 0.80 MAOB (0.66) MAPTPPARGPPARDPPARACYP1B1
SCHEMBL15163370 0.80 PPARA (0.57) MAPTCXCL12PPARGPPARDPPARA
SCHEMBL15163369 0.80 PPARA (0.57) MAPTCXCL12PPARGPPARDPPARA
SCHEMBL13869121 0.78 PTGS2 (0.72) MAPTCXCL12CYP1B1CYP1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
EP-1701938-B1 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME GENFIT (FR) 2012-07-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885CXCL12 399/4885TUBB1 3042/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885CXCL12 287/4885TUBB1 2558/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885CXCL12 287/4885TUBB1 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback