Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | RXRG | P48443 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073527 | 1.00 | KMT2A (0.56) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL31073526 | 1.00 | KMT2A (0.56) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL2614898 | 0.82 | KMT2A (0.57) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL13638236 | 0.81 | KMT2A (0.55) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL19686555 | 0.79 | KMT2A (0.54) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL62021 | 0.79 | POLB (0.53) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL9538339 | 0.78 | KMT2A (0.62) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL11001844 | 0.78 | MEN1 (0.41) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL12781970 | 0.78 | MEN1 (0.41) | KMT2AMEN1GAASMN1; SMN2HTT | |
| SCHEMBL11371064 | 0.78 | KMT2A (0.53) | KMT2AMEN1GAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12264161-B2 | Heterocyclic adenosine receptor antagonists | EXELIXIS, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| US-20230382917-A1 | Heterocyclic Adenosine Receptor Antagonists | EXELIXIS, INC. | 2023-11-30 | — | — | US | disclosed |
| US-20230382917-A1 | Heterocyclic Adenosine Receptor Antagonists | EXELIXIS, INC. | 2023-11-30 | — | — | US | disclosed |
| US-20230382917-A1 | Heterocyclic Adenosine Receptor Antagonists | EXELIXIS, INC. | 2023-11-30 | — | — | US | disclosed |
| US-11718622-B2 | Heterocyclic adenosine receptor antagonists | EXELIXIS INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11718622-B2 | Heterocyclic adenosine receptor antagonists | EXELIXIS INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11718622-B2 | Heterocyclic adenosine receptor antagonists | EXELIXIS INC. (US) | 2023-08-08 | — | — | US | disclosed |
| EP-3611174-B1 | [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE DERIVATIVE AS A2A RECEPTOR INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2022-06-08 | — | — | EP | disclosed |
| US-20210292332-A1 | Heterocyclic Adenosine Receptor Antagonists | EXELIXIS, INC. | 2021-09-23 | — | — | US | disclosed |
| US-20210292332-A1 | Heterocyclic Adenosine Receptor Antagonists | EXELIXIS, INC. | 2021-09-23 | — | — | US | disclosed |
| EP-0121341-B1 | TRIAZOLO(4,3-C)PYRIMIDINES AND TRIAZOLO(1,5-C)PYRIMIDINES SUBSTITUTED BY NITROGEN-CONTAINING HETEROCYCLIC RINGS | RIKER LABORATORIES, INCORPORATED (US) | 1988-11-17 | — | — | EP | disclosed |
| US-4612375-A | Substituted 4-hydrazino-pyrimides as intermediates for triazolo [4,3-c]pyrimidines | RIKER LABORATORIES, INC. (US) | 1986-09-16 | — | — | US | disclosed |
| US-4572910-A | BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1986-02-25 | — | — | US | disclosed |
| US-4536579-A | BRONCHODILATING AGENTS | RIKER LABORATORIES, INC. (US) | 1985-08-20 | — | — | US | disclosed |
| US-4532242-A | Bronchodilator agents | RIKER LABORATORIES, INC. (US) | 1985-07-30 | — | — | US | disclosed |
| US-4528288-A | Substituted triazolo[1,5-c]pyrimidines | RIKER LABORATORIES, INC. (US) | 1985-07-09 | — | — | US | disclosed |
| US-4477450-A | BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0121341-A1 | Triazolo(4,3-c)pyrimidines and triazolo(1,5-c)pyrimidines substituted by nitrogen-containing heterocyclic rings | RIKER LABORATORIES, INCORPORATED (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0021939-B1 | HYDRAZINO (OR AZIDO) 5-ALKYLTHIO PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USES AS HERBICIDES AND FONGICIDES | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1983-01-12 | — | — | EP | disclosed |
| EP-0021939-A1 | Hydrazino (or azido) 5-alkylthio pyrimidines, processes for their preparation and their uses as herbicides and fongicides | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292332-A1 | Heterocyclic Adenosine Receptor Antagonists | ADORA2A, ADORA1, ADORA3 | KMT2A 3650/4885MEN1 4346/4885GAA 1187/4885 |
| US-20230382917-A1 | Heterocyclic Adenosine Receptor Antagonists | ADORA2A, ADORA1, ADORA3 | KMT2A 3650/4885MEN1 4346/4885GAA 1187/4885 |
| US-11718622-B2 | Heterocyclic adenosine receptor antagonists | ADORA2A, ADORA1, ADORA3 | KMT2A 3650/4885MEN1 4346/4885GAA 1187/4885 |
| US-12264161-B2 | Heterocyclic adenosine receptor antagonists | ADORA2A, ADORA1, ADORA3 | KMT2A 3650/4885MEN1 4346/4885GAA 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.