SCHEMBL30383618

SCHEMBL30383618

CCOc1ccccc1OCc1cc(/C=C/C(=O)c2ccc(O)cc2)ccc1OC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.71
▸ KMT2A Q03164 6/20 0.71
▸ LMNA P02545 6/20 0.71
▸ ALDH1A1 P00352 3/20 0.71
▸ KDM4E B2RXH2 3/20 0.71
▸ MAPT P10636 5/20 0.69
▸ NPC1 O15118 1/20 0.69
▸ RAB9A P51151 1/20 0.69
▸ THRB P10828 1/20 0.68
▸ SMN1; SMN2 Q16637 1/20 0.68
▸ POLB P06746 1/20 0.61
▸ RECQL P46063 1/20 0.59
▸ PDE4A P27815 1/20 0.59
▸ PDE4B Q07343 1/20 0.59
▸ PDE4C Q08493 1/20 0.59
▸ PDE4D Q08499 1/20 0.59
▸ CTSL P07711 1/20 0.58
▸ ABCG2 Q9UNQ0 2/20 0.56
▸ MAOB P27338 2/20 0.56
▸ CA1 P00915 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25199616 1.00 MEN1 (0.71) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25217693 0.89 RECQL (0.74) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383576 0.88 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25201192 0.88 MEN1 (0.88) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30382823 0.88 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25185007 0.88 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25197334 0.88 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30384740 0.88 MEN1 (0.88) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25238573 0.88 MAPT (0.80) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25193937 0.88 MAPT (0.80) MEN1KMT2ALMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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