SCHEMBL25217693

SCHEMBL25217693

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1COc1ccccc1C

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.74
▸ MEN1 O00255 7/20 0.71
▸ KMT2A Q03164 7/20 0.71
▸ LMNA P02545 4/20 0.71
▸ ALDH1A1 P00352 4/20 0.71
▸ KDM4E B2RXH2 2/20 0.71
▸ MAPT P10636 6/20 0.68
▸ SMN1; SMN2 Q16637 2/20 0.68
▸ THRB P10828 1/20 0.68
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ CTSL P07711 1/20 0.58
▸ POLB P06746 1/20 0.57
▸ ABCG2 Q9UNQ0 1/20 0.54
▸ MAOB P27338 1/20 0.54
▸ NPC1 O15118 1/20 0.54
▸ RAB9A P51151 1/20 0.54
▸ CA1 P00915 1/20 0.54
▸ CA2 P00918 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25279687 0.92 MAPT (0.72) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL30382969 0.92 MAPT (0.72) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL25201205 0.92 MAPT (0.72) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL25199616 0.89 MEN1 (0.71) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL30382606 0.89 MEN1 (0.71) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL25217936 0.89 MEN1 (0.71) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL30383618 0.89 MEN1 (0.71) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL25201192 0.88 MEN1 (0.88) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL25202171 0.88 MEN1 (0.67) RECQLMEN1KMT2ALMNAALDH1A1
SCHEMBL25197334 0.88 MEN1 (0.70) RECQLMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B RECQL 2508/4885MEN1 3367/4885KMT2A 2792/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 RECQL 2196/4885MEN1 2457/4885KMT2A 3188/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 RECQL 2196/4885MEN1 2457/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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