SCHEMBL30382823

SCHEMBL30382823

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1COc1ccccc1Br

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.70
▸ KMT2A Q03164 6/20 0.70
▸ LMNA P02545 4/20 0.70
▸ ALDH1A1 P00352 3/20 0.70
▸ KDM4E B2RXH2 2/20 0.70
▸ MAPT P10636 5/20 0.67
▸ THRB P10828 1/20 0.67
▸ SMN1; SMN2 Q16637 1/20 0.67
▸ CTSL P07711 2/20 0.67
▸ RECQL P46063 1/20 0.58
▸ ABCG2 Q9UNQ0 1/20 0.53
▸ MAOB P27338 1/20 0.53
▸ NPC1 O15118 1/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ CA1 P00915 1/20 0.53
▸ CA2 P00918 1/20 0.53
▸ CXCL12 P48061 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ PTPN1 P18031 1/20 0.51
▸ DPP4 P27487 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25185007 1.00 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383618 0.88 MEN1 (0.71) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25199616 0.88 MEN1 (0.71) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25217693 0.88 RECQL (0.74) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25193991 0.88 CTSL (0.67) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383924 0.88 CTSL (0.67) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25200457 0.88 CTSL (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383439 0.88 CTSL (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25201192 0.88 MEN1 (0.88) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25197334 0.88 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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