SCHEMBL303837

SCHEMBL303837

C#CCN1C(=O)COc2cc(F)c(NC(=O)C3=C(C(N)=O)CCCC3)cc21

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
CHRM1 P11229 1/20 0.35
DHODH Q02127 2/20 0.34
NR4A1 P22736 1/20 0.34
NR4A2 P43354 1/20 0.34
MAPK8 P45983 1/20 0.33
MAPK10 P53779 1/20 0.33
ITGB3 P05106 2/20 0.33
ITGA2B P08514 2/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15942289 0.90 NPC1 (0.33) POLBITGB3ITGA2B
SCHEMBL15942288 0.90 POLB (0.32) POLBITGB3ITGA2B
SCHEMBL15941342 0.89 POLB (0.37) POLBCHRM1ITGB3ITGA2B
SCHEMBL15942093 0.89 ALOX15 (0.35) POLBTP53
SCHEMBL15942200 0.88 CHRM1 (0.37) POLBCHRM1ITGB3ITGA2B
SCHEMBL15942150 0.88 CHRM1 (0.40) POLBCHRM1ITGB3ITGA2B
SCHEMBL15941319 0.86 CHRM1 (0.42) POLBCHRM1ITGB3ITGA2BTP53
SCHEMBL15942457 0.85 CHRM1 (0.39) POLBCHRM1ITGB3ITGA2BTP53
SCHEMBL15941182 0.84 CHRM1 (0.45) POLBCHRM1TP53
SCHEMBL15941287 0.84 CHRM1 (0.45) POLBCHRM1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1741339-B1 Pesticidal composition SUMITOMO CHEMICAL CO (JP) 2014-03-19 EP claimed
US-8399380-B2 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US claimed
US-20120245030-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-27 US claimed
US-8093184-B2 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-10 US claimed
US-20100304970-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-02 US claimed
US-20100255993-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED OF (JP) 2010-10-07 US claimed
EP-1430776-B1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL CO (JP) 2010-07-14 EP claimed
US-7598207-B2 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-06 US claimed
US-20070254810-A1 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2007-11-01 US claimed
US-7205260-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-17 US claimed
US-20070066486-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2007-03-22 US claimed
EP-1741339-A1 Pesticidal composition Sumitomo Chemical Company, Limited (JP) 2007-01-10 EP claimed
US-20060240986-A1 Herbicidal method SUMITOMO CHEMICAL COMPANY, LIMITED 2006-10-26 US claimed
US-20050101488-A1 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2005-05-12 US claimed
US-20040235661-A1 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-25 US claimed
EP-1430776-A1 HERBICIDE COMPOSITION Sumitomo Chemical Company, Limited (JP) 2004-06-23 EP claimed
US-6001774-A Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-14 US claimed
JP-10231225-A None JP disclosed
CN-1200877-A Herbicidal composition SUMITOMO CHEM IND (JP) 1998-12-09 CN disclosed
JP-H10231225-A HERBICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1998-09-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254810-A1 Herbicidal composition DDT, CYP4X1, CNDP2 POLB 2308/4885CHRM1 85/4885DHODH 506/4885
US-20070066486-A1 Pesticidal composition PHOSPHO1, PTMS, PGLS POLB 1382/4885CHRM1 1891/4885DHODH 2562/4885
US-20040235661-A1 Herbicide composition DDT, CBR3, CNPY2 POLB 1887/4885CHRM1 487/4885DHODH 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.