Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | ACHE | P22303 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25209799 | 1.00 | MAOB (0.66) | MAOBMAOAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25207818 | 0.90 | MAOB (0.71) | MAOBMAOAALDH1A1MAPTKMT2A | |
| SCHEMBL30383204 | 0.90 | MAOB (0.71) | MAOBMAOAALDH1A1MAPTKMT2A | |
| SCHEMBL25193666 | 0.88 | MAOB (0.71) | MAOBMAOAKDM4EALDH1A1MAPT | |
| SCHEMBL25234108 | 0.86 | MAOA (0.58) | MAOBMAOABCHEACHE | |
| SCHEMBL30383044 | 0.86 | MAOA (0.58) | MAOBMAOABCHEACHE | |
| SCHEMBL30384245 | 0.86 | ABCG2 (0.57) | MAOBMAOABCHEACHEABCG2 | |
| SCHEMBL25284515 | 0.86 | ABCG2 (0.57) | MAOBMAOABCHEACHEABCG2 | |
| SCHEMBL21457379 | 0.84 | ALDH1A1 (0.74) | MAOBMAOAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21457374 | 0.84 | ALDH1A1 (0.74) | MAOBMAOAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |