Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.60 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204113 | 1.00 | MAPT (0.63) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL25278517 | 1.00 | MAPT (0.63) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL30383691 | 1.00 | MAPT (0.63) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL25184985 | 1.00 | MAPT (0.63) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL25279664 | 0.90 | KDM4E (0.64) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL30382661 | 0.90 | KDM4E (0.64) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL25279161 | 0.89 | MAPT (0.60) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL30383963 | 0.89 | MAPT (0.60) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL25195693 | 0.87 | MAPT (0.82) | MAPTLMNAKDM4ECXCL12TUBB4A | |
| SCHEMBL25192718 | 0.87 | MAPT (0.82) | MAPTLMNAKDM4ECXCL12TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |