SCHEMBL25204113

SCHEMBL25204113

COC(=O)COc1ccc(C(=O)/C=C/c2ccc(OC)c(O)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.63
▸ LMNA P02545 3/20 0.63
▸ KDM4E B2RXH2 3/20 0.63
▸ CXCL12 P48061 1/20 0.60
▸ TUBB4A P04350 1/20 0.60
▸ TUBB P07437 1/20 0.60
▸ TUBA3C P0DPH7 1/20 0.60
▸ TUBA1B P68363 1/20 0.60
▸ TUBA4A P68366 1/20 0.60
▸ TUBB4B P68371 1/20 0.60
▸ TUBB3 Q13509 1/20 0.60
▸ TUBB2A Q13885 1/20 0.60
▸ TUBB8 Q3ZCM7 1/20 0.60
▸ TUBA3E Q6PEY2 1/20 0.60
▸ TUBA1A Q71U36 1/20 0.60
▸ TUBA1C Q9BQE3 1/20 0.60
▸ TUBB6 Q9BUF5 1/20 0.60
▸ TUBB2B Q9BVA1 1/20 0.60
▸ TUBB1 Q9H4B7 1/20 0.60
▸ CALM1 P0DP23 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383733 1.00 MAPT (0.63) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL25278517 1.00 MAPT (0.63) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL30383691 1.00 MAPT (0.63) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL25184985 1.00 MAPT (0.63) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL25279664 0.90 KDM4E (0.64) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL30382661 0.90 KDM4E (0.64) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL25279161 0.89 MAPT (0.60) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL30383963 0.89 MAPT (0.60) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL25195693 0.87 MAPT (0.82) MAPTLMNAKDM4ECXCL12TUBB4A
SCHEMBL25192718 0.87 MAPT (0.82) MAPTLMNAKDM4ECXCL12TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885LMNA 1180/4885KDM4E 1732/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885LMNA 1817/4885KDM4E 2652/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885LMNA 1817/4885KDM4E 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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