SCHEMBL30383752

SCHEMBL30383752

O=C(/C=C/c1cccc(O)c1)c1ccc(O)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.79
KMT2A Q03164 6/20 0.79
CYP3A4 P08684 5/20 0.79
TDP1 Q9NUW8 4/20 0.79
MAPT P10636 4/20 0.79
HPGD P15428 4/20 0.79
ALOX15 P16050 4/20 0.79
MAPK1 P28482 4/20 0.79
HSD17B10 Q99714 3/20 0.79
ALDH1A1 P00352 3/20 0.79
SMN1; SMN2 Q16637 2/20 0.79
KDM4E B2RXH2 1/20 0.79
THRB P10828 1/20 0.79
MAOA P21397 2/20 0.77
MAOB P27338 2/20 0.77
HSP90AA1 P07900 1/20 0.77
ABCG2 Q9UNQ0 5/20 0.77
NR1H4 Q96RI1 1/20 0.77
NFKB1 P19838 4/20 0.73
NFKB2 Q00653 3/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25194592 1.00 MEN1 (0.79) MEN1KMT2ACYP3A4TDP1MAPT
SCHEMBL14027262 1.00 MEN1 (0.79) MEN1KMT2ACYP3A4TDP1MAPT
Methyl Alcohol SCHEMBL25196695 0.97 ABCG2 (0.78) MEN1KMT2ACYP3A4TDP1MAPT
SCHEMBL28093997 0.95 MEN1 (0.82) MEN1KMT2ACYP3A4TDP1MAPT
SCHEMBL25195193 0.95 MEN1 (0.82) MEN1KMT2ACYP3A4TDP1MAPT
2',4'-Dihydroxychalcone SCHEMBL25200440 0.89 MAPT (1.00) MEN1KMT2ACYP3A4TDP1MAPT
2',4'-Dihydroxychalcone SCHEMBL127341 0.89 MAPT (1.00) MEN1KMT2ACYP3A4TDP1MAPT
2',4'-Dihydroxychalcone SCHEMBL1411695 0.89 MAPT (1.00) MEN1KMT2ACYP3A4TDP1MAPT
SCHEMBL9702245 0.88 CYP3A4 (0.71) MEN1KMT2ACYP3A4TDP1MAPT
SCHEMBL9702240 0.88 CYP3A4 (0.71) MEN1KMT2ACYP3A4TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MEN1 3367/4885KMT2A 2792/4885CYP3A4 928/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885CYP3A4 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.