Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204454 | 1.00 | MEN1 (0.64) | MEN1KMT2ALMNACYP19A1ALDH1A1 | |
| SCHEMBL25279648 | 0.93 | MEN1 (0.74) | MEN1KMT2ALMNACYP19A1ALDH1A1 | |
| SCHEMBL25199626 | 0.90 | CYP19A1 (0.62) | MEN1KMT2ALMNACYP19A1ALDH1A1 | |
| SCHEMBL30385108 | 0.90 | CYP19A1 (0.62) | MEN1KMT2ALMNACYP19A1ALDH1A1 | |
| SCHEMBL25193206 | 0.89 | MEN1 (0.76) | MEN1KMT2ALMNACYP19A1ALDH1A1 | |
| SCHEMBL31233118 | 0.87 | MEN1 (0.79) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL25234886 | 0.87 | MEN1 (0.79) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL25201055 | 0.87 | MEN1 (0.79) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL25280287 | 0.86 | CYP19A1 (0.64) | MEN1KMT2ALMNACYP19A1ALDH1A1 | |
| SCHEMBL25196219 | 0.86 | CYP19A1 (0.67) | MEN1KMT2ALMNACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |