SCHEMBL25193206

SCHEMBL25193206

COc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1COc1ccc(F)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.76
▸ KMT2A Q03164 8/20 0.76
▸ ALDH1A1 P00352 4/20 0.76
▸ LMNA P02545 4/20 0.76
▸ KDM4E B2RXH2 1/20 0.76
▸ CYP19A1 P11511 1/20 0.66
▸ CTSL P07711 4/20 0.64
▸ ABCG2 Q9UNQ0 4/20 0.64
▸ MAPT P10636 3/20 0.64
▸ HPGD P15428 3/20 0.64
▸ TDP1 Q9NUW8 2/20 0.64
▸ TP53 P04637 2/20 0.64
▸ CYP3A4 P08684 2/20 0.64
▸ ALOX15 P16050 2/20 0.64
▸ MAPK1 P28482 2/20 0.64
▸ SMN1; SMN2 Q16637 2/20 0.64
▸ ALOX12 P18054 1/20 0.64
▸ NFKB1 P19838 1/20 0.61
▸ NFKB2 Q00653 1/20 0.61
▸ RELA Q04206 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25214881 0.93 MEN1 (0.71) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25221504 0.91 CYP19A1 (0.67) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL31233302 0.90 CYP19A1 (0.66) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL30383612 0.90 CTSL (0.67) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25219723 0.90 CYP19A1 (0.66) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25285110 0.90 CYP19A1 (0.66) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25190643 0.90 CTSL (0.67) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25197331 0.90 CYP19A1 (0.68) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25199723 0.89 CYP19A1 (0.64) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL25204454 0.89 MEN1 (0.64) MEN1KMT2AALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MEN1 3367/4885KMT2A 2792/4885ALDH1A1 3285/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885ALDH1A1 3081/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885ALDH1A1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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