Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 3/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484275 | 1.00 | LMNA (0.55) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3484270 | 1.00 | LMNA (0.55) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3484239 | 0.89 | P4HB (0.60) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3484234 | 0.89 | P4HB (0.60) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL30383580 | 0.89 | P4HB (0.60) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3484280 | 0.89 | LMNA (0.53) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3484282 | 0.89 | LMNA (0.53) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3483817 | 0.88 | MAPT (0.63) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL30382898 | 0.88 | MAPT (0.63) | LMNANPSR1MAPTMEN1KMT2A | |
| SCHEMBL3483818 | 0.88 | MAPT (0.63) | LMNANPSR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |