Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | APP | P05067 | 5/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491085 | 1.00 | CYP3A4 (0.63) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL814529 | 0.94 | MEN1 (0.69) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL25198434 | 0.94 | MEN1 (0.69) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL25216289 | 0.92 | MAOB (0.70) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL815468 | 0.92 | MAOB (0.70) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL30384569 | 0.90 | ABCG2 (0.56) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL25208708 | 0.90 | ABCG2 (0.56) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL814852 | 0.90 | ABCG2 (0.56) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL30383108 | 0.90 | ABCG2 (0.56) | CYP3A4MAPTLMNAMEN1MAPK1 | |
| SCHEMBL25212652 | 0.89 | XDH (0.52) | CYP3A4MAPTLMNAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |