SCHEMBL25216289

SCHEMBL25216289

CC(C)(Oc1ccc(C(=O)C=Cc2ccc(Cl)cc2)c(O)c1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.70
ABCG2 Q9UNQ0 6/20 0.70
MAOA P21397 3/20 0.63
PPARA Q07869 2/20 0.62
MAPT P10636 4/20 0.58
LMNA P02545 3/20 0.58
MEN1 O00255 3/20 0.58
CYP3A4 P08684 3/20 0.58
KMT2A Q03164 3/20 0.58
MAPK1 P28482 2/20 0.58
APP P05067 2/20 0.58
CYP2C19 P33261 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NPC1 O15118 1/20 0.56
RECQL P46063 1/20 0.56
RAB9A P51151 1/20 0.56
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 1/20 0.56
TP53 P04637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815468 1.00 MAOB (0.70) MAOBABCG2MAOAPPARAMAPT
SCHEMBL8752262 0.93 PPARA (0.67) MAOBABCG2MAOAPPARAMAPT
SCHEMBL25199613 0.93 PPARA (0.67) MAOBABCG2MAOAPPARAMAPT
SCHEMBL14491085 0.92 CYP3A4 (0.63) MAOBABCG2MAOAPPARAMAPT
SCHEMBL30384412 0.92 CYP3A4 (0.63) MAOBABCG2MAOAPPARAMAPT
SCHEMBL25198434 0.88 MEN1 (0.69) MAOBABCG2MAOAPPARAMAPT
SCHEMBL814529 0.88 MEN1 (0.69) MAOBABCG2MAOAPPARAMAPT
SCHEMBL25208708 0.86 ABCG2 (0.56) MAOBABCG2MAOAPPARAMAPT
SCHEMBL30383108 0.86 ABCG2 (0.56) MAOBABCG2MAOAPPARAMAPT
SCHEMBL30384569 0.86 ABCG2 (0.56) MAOBABCG2MAOAPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885ABCG2 1606/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.