Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521730 | 0.86 | NR3C1 (1.00) | NR3C1NR3C2 | |
| SCHEMBL14944428 | 0.85 | NR3C1 (0.54) | NR3C1NR3C2 | |
| SCHEMBL5518557 | 0.84 | NR3C1 (0.89) | NR3C1NR3C2 | |
| SCHEMBL5521600 | 0.83 | NR3C1 (1.00) | NR3C1NR3C2 | |
| SCHEMBL4403193 | 0.83 | NR3C1 (0.66) | NR3C1NR3C2 | |
| SCHEMBL5524371 | 0.82 | NR3C2 (0.78) | NR3C1NR3C2 | |
| SCHEMBL4223472 | 0.82 | NR3C1 (0.65) | NR3C1NR3C2 | |
| SCHEMBL303967 | 0.82 | NR3C1 (0.65) | NR3C1NR3C2 | |
| SCHEMBL304525 | 0.82 | NR3C1 (0.65) | NR3C1NR3C2 | |
| SCHEMBL5524991 | 0.81 | NR3C1 (0.83) | NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869003-B1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2013-05-15 | — | — | EP | disclosed |
| US-8093281-B2 | Indazoles as glucocorticoid receptor ligands | GLAXO GROUP LIMITED (GB) | 2012-01-10 | — | — | US | disclosed |
| US-8093281-B2 | Indazoles as glucocorticoid receptor ligands | GLAXO GROUP LIMITED (GB) | 2012-01-10 | — | — | US | disclosed |
| US-8093281-B2 | Indazoles as glucocorticoid receptor ligands | GLAXO GROUP LIMITED (GB) | 2012-01-10 | — | — | US | disclosed |
| US-20090074675-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| US-20090074675-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| US-20090074675-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| US-20080207725-A1 | Phenyl-Pyrazole Derivatives as Non-Steroidal Glucocorticoid Receptor Ligands | GLAXO GROUP LIMITED, A CORPORATION | 2008-08-28 | — | — | US | disclosed |
| US-20080207725-A1 | Phenyl-Pyrazole Derivatives as Non-Steroidal Glucocorticoid Receptor Ligands | GLAXO GROUP LIMITED, A CORPORATION | 2008-08-28 | — | — | US | disclosed |
| US-20080207725-A1 | Phenyl-Pyrazole Derivatives as Non-Steroidal Glucocorticoid Receptor Ligands | GLAXO GROUP LIMITED, A CORPORATION | 2008-08-28 | — | — | US | disclosed |
| WO-2007000334-A1 | PHENYL-PYRAZOLE DERIVATIVES AS NON-STEROIDAL GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074675-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | NR3C1, NR3C2, MC2R | NR3C1 1/4885NR3C2 2/4885 |
| US-20080207725-A1 | Phenyl-Pyrazole Derivatives as Non-Steroidal Glucocorticoid Receptor Ligands | NR3C1, NR3C2, NR5A1 | NR3C1 1/4885NR3C2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.