Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.39 |
| ▸ | TTK | P33981 | 12/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.33 |
| ▸ | SIK1 | P57059 | 1/20 | 0.32 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.32 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123734 | 0.93 | PTK2 (0.40) | PTK6TTKPTK2JAK2JAK1 | |
| SCHEMBL30171937 | 0.93 | PTK2 (0.40) | PTK6TTKPTK2JAK2JAK1 | |
| SCHEMBL24870930 | 0.92 | PTK2 (0.38) | PTK6TTKPTK2JAK2JAK1 | |
| SCHEMBL30172036 | 0.92 | PTK2 (0.38) | PTK6TTKPTK2JAK2JAK1 | |
| SCHEMBL25450886 | 0.91 | TTK (0.34) | PTK6TTK | |
| SCHEMBL30385630 | 0.89 | GPR119 (0.37) | PTK6JAK2JAK1 | |
| SCHEMBL24112482 | 0.89 | PTK6 (0.34) | PTK6TTK | |
| SCHEMBL22122917 | 0.88 | PTK6 (0.45) | PTK6TTKJAK2JAK1AURKB | |
| SCHEMBL30385387 | 0.88 | PTK6 (0.45) | PTK6TTKJAK2JAK1AURKB | |
| Formic Acid SCHEMBL30385529 | 0.88 | TTK (0.33) | PTK6TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |