Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TPI1 | P60174 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068126 | 0.89 | TPI1 (0.41) | ALDH1A1LPAR3LPAR1LPAR2TPI1 | |
| SCHEMBL16368268 | 0.87 | ALDH1A1 (0.56) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL16647537 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL14283709 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL38660105 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SOAT1LPAR3LPAR1LPAR2 | |
| SCHEMBL17753927 | 0.80 | TPI1 (0.40) | LPAR3LPAR1LPAR2TPI1ENPP2 | |
| SCHEMBL30384633 | 0.79 | TSHR (0.36) | ALDH1A1LPAR3LPAR1LPAR2TPI1 | |
| SCHEMBL16333381 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Phosphoric Acid SCHEMBL28164744 | 0.79 | ALDH1A1 (0.72) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL3750750 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022881-B | Inhibitors of CD 73-mediated immunosuppression | 艾库斯生物科学有限公司 | 2023-05-02 | — | — | CN | disclosed |