SCHEMBL3038523

SCHEMBL3038523

CC(C)Oc1ccccc1.O=S(=O)(Cl)Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
ALDH1A1 P00352 3/20 0.49
GAA P10253 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
ALDH1A3 P47895 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
CNR2 P34972 3/20 0.44
KAT6A Q92794 1/20 0.44
PARP10 Q53GL7 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394 0.86 KMT2A (0.54) KMT2AALDH1A1GAAMEN1LMNA
Ammonia Solution, Strong SCHEMBL8909178 0.84 KMT2A (0.52) KMT2AALDH1A1GAAMEN1LMNA
Phosphine SCHEMBL28772208 0.84 KMT2A (0.52) KMT2AALDH1A1GAAMEN1LMNA
Hydrogen Sulfide SCHEMBL27992657 0.84 KMT2A (0.52) KMT2AALDH1A1GAAMEN1LMNA
Hydrochloric Acid SCHEMBL6570767 0.81 KMT2A (0.50) KMT2AALDH1A1GAAMEN1LMNA
Ethylene SCHEMBL28227817 0.81 KMT2A (0.50) KMT2AALDH1A1GAAMEN1LMNA
Methylamine SCHEMBL27820445 0.81 KMT2A (0.50) KMT2AALDH1A1GAAMEN1LMNA
SCHEMBL7959053 0.81 CYP1A2 (0.41) KMT2AALDH1A1GAAMEN1LMNA
SCHEMBL28153666 0.79 KMT2A (0.49) KMT2AALDH1A1GAAMEN1LMNA
SCHEMBL27469399 0.79 LMNA (0.53) KMT2AGAAMEN1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047699-A Preparation method of 4-isopropoxy benzenesulfonyl chloride 武威广达科技有限公司 2024-05-17 CN claimed
CN-121779283-A Process for synthesizing 4-isopropoxy benzenesulfonyl chloride 大连双硼医药化工有限公司 2026-04-03 CN disclosed
CN-118047699-A Preparation method of 4-isopropoxy benzenesulfonyl chloride 武威广达科技有限公司 2024-05-17 CN disclosed
CN-106463627-B Photovoltaic element 东丽株式会社 2019-06-28 CN disclosed
CN-106892920-A Aloperine derivative, preparation method and application thereof 中国医学科学院医药生物技术研究所 2017-06-27 CN disclosed
CN-104520288-B Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists 坎莫森特里克斯公司 2017-05-17 CN disclosed
CN-106463627-A Photovoltaic element 东丽株式会社 2017-02-22 CN disclosed
CN-106008288-A Benzsulfamide compound and application thereof 西北农林科技大学 2016-10-12 CN disclosed
CN-103265501-B Method for producing N-phenyl-N'-phenylsulfonylpiperazine derivative SHIONOGI & CO 2015-06-03 CN disclosed
CN-104520288-A Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists CHEMOCENTRYX 2015-04-15 CN disclosed
US-20070149603-A1 PPAR ACTIVE COMPOUNDS PLEXXIKON, INC. 2007-06-28 US disclosed
US-7202266-B2 PPAR active compounds PLEXXIKON, INC. (US) 2007-04-10 US disclosed
CN-1845898-A PPAR active compounds PLEXXIKON INC (US) 2006-10-11 CN disclosed
EP-1648867-A1 PPAR ACTIVE COMPOUNDS PLEXXIKON, INC. (US) 2006-04-26 EP disclosed
US-20050288354-A1 PPAR active compounds PLEXXIKON, INC. 2005-12-29 US disclosed
CN-1711257-A Aryl sulfonamides CHEMOCENTRYX (US) 2005-12-21 CN disclosed
CN-1617855-A Cytosolic phospholipase A2Inhibitors WYETH CORP (US) 2005-05-18 CN disclosed
US-20050038246-A1 PPAR active compounds PLEXXIKON, INC. 2005-02-17 US disclosed
WO-2005009958-A1 PPAR ACTIVE COMPOUNDS PLEXXIKON, INC. (US) 2005-02-03 WO disclosed
CN-86100964-A The preparation method of piperidine compounds 1986-10-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038246-A1 PPAR active compounds PPARG, PPARD, PPARA KMT2A 3773/4885ALDH1A1 1171/4885GAA 1372/4885
US-20050288354-A1 PPAR active compounds PPARG, PPARD, PPARA KMT2A 3773/4885ALDH1A1 1171/4885GAA 1372/4885
US-20070149603-A1 PPAR ACTIVE COMPOUNDS PPARG, PPARD, PPARA KMT2A 3773/4885ALDH1A1 1171/4885GAA 1372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.