Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394 | 0.97 | KMT2A (0.54) | KMT2AALDH1A1LMNAGAAMEN1 | |
| Phosphine SCHEMBL28772208 | 0.94 | KMT2A (0.52) | KMT2AALDH1A1LMNAGAAMEN1 | |
| Hydrogen Sulfide SCHEMBL27992657 | 0.94 | KMT2A (0.52) | KMT2AALDH1A1LMNAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL6570767 | 0.92 | KMT2A (0.50) | KMT2AALDH1A1LMNAGAAMEN1 | |
| Methylamine SCHEMBL27820445 | 0.92 | KMT2A (0.50) | KMT2AALDH1A1LMNAGAAMEN1 | |
| Ethylene SCHEMBL28227817 | 0.92 | KMT2A (0.50) | KMT2AALDH1A1LMNAGAAMEN1 | |
| SCHEMBL28153666 | 0.90 | KMT2A (0.49) | KMT2AALDH1A1LMNAGAAMEN1 | |
| SCHEMBL9658587 | 0.87 | LTA4H (0.57) | KMT2AALDH1A1LMNAGAAMEN1 | |
| SCHEMBL12960634 | 0.87 | KMT2A (0.52) | KMT2AALDH1A1LMNAGAAMEN1 | |
| Anisole SCHEMBL28836834 | 0.87 | CA4 (0.67) | KMT2AALDH1A1LMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |