Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 10/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25450699 | 0.96 | TTK (0.37) | TTKPTK6EGFRAURKAMAP3K7 | |
| SCHEMBL24112408 | 0.93 | TTK (0.36) | TTKPTK6EGFRAURKAMAP3K7 | |
| SCHEMBL25450694 | 0.90 | PTK6 (0.40) | TTKPTK6EGFRAURKA | |
| SCHEMBL22123694 | 0.88 | TTK (0.41) | TTKPTK6MAP3K7CYP3A4CYP2C9 | |
| SCHEMBL30172065 | 0.88 | TTK (0.41) | TTKPTK6MAP3K7CYP3A4CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL28982207 | 0.86 | PTK6 (0.36) | TTKPTK6 | |
| SCHEMBL25173551 | 0.85 | GPR119 (0.38) | TTKPTK6 | |
| Trifluoroacetic Acid SCHEMBL30386113 | 0.84 | PTK6 (0.39) | PTK6BRAFEGFRAURKA | |
| SCHEMBL25450726 | 0.82 | PTK6 (0.38) | TTKPTK6 | |
| SCHEMBL22124340 | 0.81 | CDK2 (0.44) | TTKPTK6AURKASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |