Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 8/20 | 0.39 |
| ▸ | BRAF | P15056 | 4/20 | 0.34 |
| ▸ | LCK | P06239 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.32 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25176442 | 0.88 | PTK6 (0.40) | PTK6LCKEGFRERBB2ERBB3 | |
| SCHEMBL22123240 | 0.88 | PTK6 (0.50) | PTK6LCKEGFRAURKB | |
| SCHEMBL30171783 | 0.88 | PTK6 (0.50) | PTK6LCKEGFRAURKB | |
| Iodide SCHEMBL28982230 | 0.88 | PTK6 (0.39) | PTK6LCKEGFRERBB2ERBB3 | |
| SCHEMBL25450694 | 0.87 | PTK6 (0.40) | PTK6LCKEGFRAURKAIGF1R | |
| SCHEMBL30385489 | 0.86 | PTK6 (0.41) | PTK6BRAFLCKERBB2 | |
| SCHEMBL24112330 | 0.85 | PTK6 (0.39) | PTK6LCKEGFRERBB2ERBB3 | |
| Trifluoroacetic Acid SCHEMBL30385325 | 0.84 | TTK (0.36) | PTK6BRAFEGFRAURKA | |
| Trifluoroacetic Acid SCHEMBL28982207 | 0.83 | PTK6 (0.36) | PTK6 | |
| SCHEMBL22123440 | 0.81 | PTK6 (0.43) | PTK6LCKAURKAAURKBMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |