Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319489 | 0.81 | MAOB (0.59) | ALDH1A1MAOB | |
| SCHEMBL14855144 | 0.78 | CCR5 (0.49) | MAOBMRGPRX4 | |
| SCHEMBL371725 | 0.77 | MAOB (0.53) | MAOBMRGPRX4CYP19A1S1PR5 | |
| Hydrochloric Acid SCHEMBL11418706 | 0.76 | MAOB (0.51) | MAOBMRGPRX4CYP19A1S1PR5 | |
| SCHEMBL20607894 | 0.75 | NPC1 (0.51) | KDM4EALDH1A1MAOBNTRK1CSF1R | |
| SCHEMBL30885393 | 0.75 | PTPRZ1 (0.68) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL5571351 | 0.72 | MAOB (0.53) | TDP1MAOBMRGPRX4CYP19A1S1PR5 | |
| SCHEMBL3321494 | 0.71 | MAOB (0.65) | MAOBMRGPRX4 | |
| SCHEMBL2565629 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1MRGPRX4 | |
| SCHEMBL13530325 | 0.70 | PTPRZ1 (0.52) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-B | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |