Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 9/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 7/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387111 | 0.94 | STING1 (0.57) | STING1NHERF1GRIK1KCNK2KCNK10 | |
| SCHEMBL28991301 | 0.94 | STING1 (0.57) | STING1NHERF1GRIK1KCNK2KCNK10 | |
| SCHEMBL30885399 | 0.89 | STING1 (0.52) | STING1SNCAKCNK2 | |
| SCHEMBL30885397 | 0.88 | STING1 (0.51) | STING1NHERF1SNCAGRIK1KCNK2 | |
| SCHEMBL30885448 | 0.86 | STING1 (0.57) | STING1GRIK1KCNK2KCNK10 | |
| SCHEMBL30885375 | 0.85 | STING1 (0.54) | STING1NHERF1SNCAGRIK1 | |
| SCHEMBL30387260 | 0.84 | STING1 (0.64) | STING1NHERF1SNCA | |
| SCHEMBL28991251 | 0.84 | STING1 (0.64) | STING1NHERF1SNCA | |
| SCHEMBL30885381 | 0.83 | STING1 (0.52) | STING1NHERF1SNCA | |
| SCHEMBL30885386 | 0.82 | STING1 (0.58) | STING1KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |