⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28070919 | 0.87 | HDAC1 (0.44) | — | |
| Pyridine SCHEMBL28192621 | 0.85 | ALDH1A1 (0.38) | — | |
| SCHEMBL18015421 | 0.83 | NPC1 (0.42) | — | |
| SCHEMBL23331493 | 0.80 | NPC1 (0.48) | — | |
| Ethoxycarbonyl Group SCHEMBL27710452 | 0.78 | MEN1 (0.44) | — | |
| SCHEMBL5867346 | 0.76 | ENPP2 (0.52) | — | |
| SCHEMBL11415743 | 0.75 | MAPT (0.47) | — | |
| SCHEMBL1772749 | 0.75 | EPHX2 (0.43) | — | |
| SCHEMBL23930009 | 0.73 | GBA1 (0.41) | — | |
| SCHEMBL1773529 | 0.73 | HDAC1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2648 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505234-B | Modified TB polymer, preparation method and application thereof in aluminum alloy surface coating | 山东大学 | 2025-06-10 | — | — | CN | claimed |
| WO-2025087337-A1 | DISSOCIATION AGENT AND KIT | 利多(香港)有限公司 | 2025-05-01 | — | — | WO | claimed |
| CN-119899825-A | Dissociating agent and kit | 利多(香港)有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119505234-A | Modified TB polymer, preparation method and application thereof in aluminum alloy surface coating | 山东大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119192071-A | Preparation method of 5-bromopyridine-2-carboxylic acid methyl ester | 济南泺合医药技术有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-117169519-B | Dissociation agent and kit for detecting TT3 and/or TT4 in sample | 艾康生物技术(杭州)有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-117169519-A | Dissociation agent and kit for detecting TT3 and/or TT4 in sample | 艾康生物技术(杭州)有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-112279806-B | Organic electrode material and preparation method and application thereof | 西南大学 | 2023-10-17 | — | — | CN | claimed |
| CN-112362432-B | Dissociation agent universally used in serum TT3 and TT4 and preparation method thereof | 广州科方生物技术股份有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-108164461-B | Total synthesis of natural product (+/-) -ylacrine and resolution method of enantiomer | 中国科学院新疆理化技术研究所 | 2021-03-09 | — | — | CN | claimed |
| CN-101560183-B | Method for preparing 5-bromo-2-methylpyridine | ZHEJIANG MED XINCHANG PHARM | 2011-02-02 | — | — | CN | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| CN-101560183-A | Method for preparing 5-bromo-2-methylpyridine | ZHEJIANG MEDICINE CO LTD (CN) | 2009-10-21 | — | — | CN | claimed |
| CN-101514184-A | Synthetic method of 5-bromo-2-methylpyridine | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-100427468-C | Apparatus and method for separating 5-bromo-2-methyl pyridine isomer by intermittent rectification under vacuum | UNIV TIANJIN (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-101193880-A | Exo-and diastereoselective synthesis of himbacine analogs | SCHERING CORP (US) | 2008-06-04 | — | — | CN | claimed |
| CN-1850803-A | Apparatus and method for separating 5-bromo-2-methyl pyridine isomer by intermittent rectification under vacuum | UNIV TIANJIN (CN) | 2006-10-25 | — | — | CN | claimed |
| EP-1292579-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2003-03-19 | — | — | EP | claimed |
| WO-2001087854-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRAZINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |