Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.46 |
| ▸ | ACLY | P53396 | 6/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545864 | 1.00 | CCR2 (0.46) | CCR2ACLYPTGES2GUSBNR3C1 | |
| SCHEMBL30286501 | 0.84 | PTGES2 (0.40) | CCR2ACLYPTGES2CA12CA1 | |
| SCHEMBL20354850 | 0.84 | PTGES2 (0.40) | CCR2ACLYPTGES2CA12CA1 | |
| SCHEMBL30286537 | 0.83 | ACLY (0.42) | CCR2ACLYPTGES2CA12CA1 | |
| SCHEMBL20355177 | 0.83 | ACLY (0.42) | CCR2ACLYPTGES2CA12CA1 | |
| SCHEMBL21545942 | 0.82 | CCR2 (0.37) | CCR2ACLYPTGES2CA12CA1 | |
| SCHEMBL30286583 | 0.82 | CCR2 (0.37) | CCR2ACLYPTGES2CA12CA1 | |
| SCHEMBL20354732 | 0.81 | CCR2 (0.42) | CCR2ACLYPTGES2NR3C1PGR | |
| SCHEMBL30286416 | 0.81 | CCR2 (0.42) | CCR2ACLYPTGES2NR3C1PGR | |
| SCHEMBL20339191 | 0.81 | POLB (0.39) | CCR2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |