Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17120406 | 0.77 | CHRNB2 (0.35) | — | |
| SCHEMBL15711294 | 0.74 | HDAC1 (0.37) | HDAC8HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL18594506 | 0.74 | HDAC1 (0.37) | HDAC8HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL5598957 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL25053039 | 0.73 | EGFR (0.44) | — | |
| SCHEMBL27348061 | 0.73 | HDAC2 (0.48) | HDAC8HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL8600653 | 0.73 | HDAC2 (0.48) | HDAC8HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL27795833 | 0.73 | HDAC2 (0.48) | HDAC8HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL19026353 | 0.72 | — | — | |
| SCHEMBL3171061 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265444-A | Nematicidal compounds, process for their preparation and their use | 华东理工大学 | 2023-06-20 | — | — | CN | disclosed |