Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29733030 | 1.00 | TDP1 (0.55) | TDP1KDM4ETSHRPOLBMAPT | |
| Hydrochloric Acid SCHEMBL11526658 | 0.98 | TDP1 (0.54) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL4961822 | 0.88 | TDP1 (0.63) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL20746628 | 0.87 | TDP1 (0.54) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL6033690 | 0.83 | KDM4E (0.67) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL4033092 | 0.82 | TDP1 (0.74) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL8772399 | 0.82 | TDP1 (0.81) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL7106696 | 0.82 | SMN1; SMN2 (0.57) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL7105171 | 0.82 | SMN1; SMN2 (0.57) | TDP1KDM4ETSHRPOLBMAPT | |
| SCHEMBL30398318 | 0.81 | TDP1 (0.49) | TDP1KDM4ETSHRPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114609074-A | Method for detecting content of cyclic amine compound in copper etching solution | 江苏和达电子科技有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-109320718-A | A kind of high barrier transparent flexible display material and preparation method thereof | 中国科学院长春应用化学研究所 | 2019-02-12 | — | — | CN | claimed |
| CN-104130184-B | The manufacture method of the compound that contains pyridine ring and halogenated methyl pyridine derivate and tetrazole radical 9 oxime derivate | 日本曹达株式会社 | 2016-06-15 | — | — | CN | claimed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-104130184-A | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO | 2014-11-05 | — | — | CN | claimed |
| US-8735586-B2 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI (FR) | 2014-05-27 | — | — | US | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-102791691-A | Compound containing pyridine ring, halogenated picoline derivative, and method for producing tetrazolyloxime derivative | NIPPON SODA CO | 2012-11-21 | — | — | CN | claimed |
| EP-2173721-B1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2011-12-28 | — | — | EP | claimed |
| EP-2173747-B1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2011-12-21 | — | — | EP | claimed |
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-10-14 | — | — | US | claimed |
| US-20100216988-A1 | Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-08-26 | — | — | US | claimed |
| EP-2173747-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | claimed |
| EP-2173721-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | claimed |
| CN-101687865-A | A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | claimed |
| CN-101687815-A | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | claimed |
| WO-2009000413-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | claimed |
| WO-2009000412-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI AVENTIS (FR) | 2008-12-31 | — | — | WO | claimed |
| US-4116968-A | PROCESS FOR THE PRODUCTION OF 2-VINYL PYRIDINE | LONZA, LTD. (CH) | 1978-09-26 | — | — | US | claimed |
| CN-114609074-A | Method for detecting content of cyclic amine compound in copper etching solution | 江苏和达电子科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-109320718-A | A kind of high barrier transparent flexible display material and preparation method thereof | 中国科学院长春应用化学研究所 | 2019-02-12 | — | — | CN | disclosed |
| CN-104220417-B | Use the method for aryl hydrazines synthesizing amino biphenyl class | 巴斯夫欧洲公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-104109150-B | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | 日本曹达株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-104072408-B | Compound containing pyridine ring and halogenated methyl pyridine derivate and the manufacture method of tetrazole radical 9 oxime derivate | 日本曹达株式会社 | 2016-09-14 | — | — | CN | disclosed |
| CN-104130184-B | The manufacture method of the compound that contains pyridine ring and halogenated methyl pyridine derivate and tetrazole radical 9 oxime derivate | 日本曹达株式会社 | 2016-06-15 | — | — | CN | disclosed |
| CN-104072483-B | The manufacture method of the compound containing pyridine ring and halogenated methyl pyridine derivate and tetrazyl 9 oxime derivate | NIPPON SODA CO., LTD. (JP) | 2016-04-13 | — | — | CN | disclosed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-102791691-B | Compound containing pyridine ring, halogenated picoline derivative, and method for producing tetrazolyloxime derivative | NIPPON SODA CO | 2015-06-03 | — | — | CN | disclosed |
| CN-104220417-A | Method for synthesising aminobiphenyls using aryl hydrazines | BASF SE | 2014-12-17 | — | — | CN | disclosed |
| CN-104130184-A | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO | 2014-11-05 | — | — | CN | disclosed |
| CN-104109150-A | Compound Containing Pyridine Ring And Method For Producing Halogenated Picoline Derivative And Tetrazolyloxime Derivative | NIPPON SODA CO | 2014-10-22 | — | — | CN | disclosed |
| CN-102143935-B | Process for producing aminobiphenyls | BASF SE (DE) | 2014-10-22 | — | — | CN | disclosed |
| CN-104072408-A | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO | 2014-10-01 | — | — | CN | disclosed |
| CN-104072483-A | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO | 2014-10-01 | — | — | CN | disclosed |
| US-8735586-B2 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI (FR) | 2014-05-27 | — | — | US | disclosed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | disclosed |
| CN-102791691-A | Compound containing pyridine ring, halogenated picoline derivative, and method for producing tetrazolyloxime derivative | NIPPON SODA CO | 2012-11-21 | — | — | CN | disclosed |
| EP-2173721-B1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2011-12-28 | — | — | EP | disclosed |
| EP-2173747-B1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2011-12-21 | — | — | EP | disclosed |
| CN-102143935-A | Process for producing aminobiphenyls | UNIV MUENCHEN TECH | 2011-08-03 | — | — | CN | disclosed |
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-10-14 | — | — | US | disclosed |
| US-20100216988-A1 | Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-08-26 | — | — | US | disclosed |
| EP-2173721-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | disclosed |
| EP-2173747-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | disclosed |
| CN-101687865-A | A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | disclosed |
| CN-101687815-A | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | disclosed |
| WO-2009000413-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000412-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| EP-0220963-B1 | ADSORPTION OF GASES BY AMINE AND PHOSPHINE COMPLEXED MN(II) COMPOUNDS | UNIVERSITY OF CINCINNATI (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4713091-A | Adsorption of gases by amine and phosphine complexed Mn(II) and compounds | UNIVERSITY OF CINCINNATI (US) | 1987-12-15 | — | — | US | disclosed |
| US-4668255-A | Adsorption of gases by amine complexed Mn (II) | UNIVERSITY OF CINCINNATI (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0220963-A2 | Adsorption of gases by amine and phosphine complexed Mn(II) compounds | UNIVERSITY OF CINCINNATI (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4515708-A | BETA-PYRIDYLETHYLAMINE | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-05-07 | — | — | US | disclosed |
| US-4196287-A | Process for the catalytic production of 2-substituted pyridines | LONZA LTD. (CH) | 1980-04-01 | — | — | US | disclosed |
| US-4159332-A | Prevention of or reduction in severity of myocardial infarction | UNIMED, INC. (US) | 1979-06-26 | — | — | US | disclosed |
| US-4116968-A | PROCESS FOR THE PRODUCTION OF 2-VINYL PYRIDINE | LONZA, LTD. (CH) | 1978-09-26 | — | — | US | disclosed |
| US-4116968-A | PROCESS FOR THE PRODUCTION OF 2-VINYL PYRIDINE | LONZA, LTD. (CH) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | AZI2, NISCH, UQCRB | TDP1 3404/4885KDM4E 1197/4885TSHR 1319/4885 |
| US-20100216988-A1 | Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | AZI2, NIT2, NISCH | TDP1 2817/4885KDM4E 478/4885TSHR 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.