Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560083 | 1.00 | KDM1A (0.49) | KDM1AGPR119YAP1F10CHRM3 | |
| SCHEMBL17554496 | 0.93 | GPR119 (0.55) | KDM1AGPR119YAP1FAAHPRMT5 | |
| SCHEMBL2195099 | 0.91 | YAP1 (0.55) | GPR119YAP1CHRM3PRMT5 | |
| SCHEMBL29796027 | 0.87 | KDM1A (0.58) | KDM1AGPR119PDE4APDE4BPDE4C | |
| SCHEMBL520668 | 0.87 | KDM1A (0.58) | KDM1AGPR119PDE4APDE4BPDE4C | |
| SCHEMBL19327832 | 0.86 | MAOB (0.52) | GPR119YAP1F10FAAHPDE4A | |
| SCHEMBL30388453 | 0.86 | MAOB (0.52) | GPR119YAP1F10FAAHPDE4A | |
| SCHEMBL19327864 | 0.85 | MAOB (0.49) | F10CHRM3FAAH | |
| SCHEMBL2556786 | 0.85 | GPR119 (0.49) | KDM1AGPR119PRMT5 | |
| SCHEMBL17554365 | 0.85 | KDM1A (0.48) | KDM1AGPR119YAP1CHRM3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189059-B1 | THIENOPYRROLES AS HISTONE DEMETHYLASE INHIBITORS | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2023-02-22 | — | — | EP | disclosed |