Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.50 |
| ▸ | NEK2 | P51955 | 1/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.46 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.46 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.46 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.46 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17574299 | 1.00 | GPR119 (0.50) | GPR119NEK2CACNB4CACNA1ACACNA1G | |
| SCHEMBL17554458 | 0.88 | GPR119 (0.56) | GPR119NEK2CACNB4CACNA1ACACNA1G | |
| SCHEMBL30389108 | 0.88 | GPR119 (0.56) | GPR119NEK2CACNB4CACNA1ACACNA1G | |
| SCHEMBL19327867 | 0.86 | LIPE (0.45) | GPR119LIPE | |
| SCHEMBL17560028 | 0.86 | GPR119 (0.49) | GPR119NEK2CACNB4CACNA1ACACNA1G | |
| SCHEMBL17560092 | 0.84 | LIPE (0.40) | LIPE | |
| SCHEMBL17554365 | 0.84 | KDM1A (0.48) | GPR119NEK2CACNB4CACNA1ACACNA1G | |
| SCHEMBL19022896 | 0.81 | GPR119 (0.55) | GPR119CHEK2 | |
| SCHEMBL19023504 | 0.81 | GPR119 (0.59) | GPR119CHEK2 | |
| SCHEMBL29419894 | 0.81 | GPR119 (0.59) | GPR119CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189059-B1 | THIENOPYRROLES AS HISTONE DEMETHYLASE INHIBITORS | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2023-02-22 | — | — | EP | disclosed |