Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536289 | 0.74 | POLB (0.45) | POLBHTTCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5999845 | 0.74 | MEN1 (0.56) | SYKSMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL31496254 | 0.74 | POLB (0.45) | POLBHTTCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL30389997 | 0.74 | MEN1 (0.56) | SYKSMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL744398 | 0.73 | BTK (0.47) | POLBSYKCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4237853 | 0.73 | SMN1; SMN2 (0.43) | SYKSMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL4271429 | 0.73 | MEN1 (0.46) | SYKSMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL31201809 | 0.73 | SMN1; SMN2 (0.43) | SYKSMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL30112542 | 0.71 | CTSK (0.40) | POLBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL30390144 | 0.71 | MEN1 (0.53) | SYKSMN1; SMN2HTTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960046-A | Preparation method of 1-amino substituted isoquinoline substances | 温州大学 | 2023-04-14 | — | — | CN | disclosed |