Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418775 | 0.86 | KRAS (0.40) | KRAS | |
| SCHEMBL25419645 | 0.86 | KRAS (0.40) | KRAS | |
| SCHEMBL29680000 | 0.83 | KRAS (0.39) | KRAS | |
| SCHEMBL29680448 | 0.81 | KRAS (0.39) | KRAS | |
| Trifluoroacetic Acid SCHEMBL29418842 | 0.80 | KRAS (0.38) | KRAS | |
| SCHEMBL29418819 | 0.76 | KRAS (0.48) | KRAS | |
| SCHEMBL30704160 | 0.76 | KRAS (0.48) | KRAS | |
| SCHEMBL31194908 | 0.74 | KRAS (0.47) | KRAS | |
| SCHEMBL31748999 | 0.73 | ROCK2 (0.43) | — | |
| SCHEMBL30391398 | 0.72 | KRAS (0.37) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182313-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |