Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.61 |
| ▸ | NPY1R | P25929 | 9/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.61 |
| ▸ | NPY2R | P49146 | 5/20 | 0.61 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123583 | 0.96 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30198606 | 0.94 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31571458 | 0.94 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL18951657 | 0.93 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13563452 | 0.93 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30516165 | 0.92 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31729537 | 0.92 | NPY4R (0.69) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29850918 | 0.92 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| Kyotorphin SCHEMBL248288 | 0.92 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| Kyotorphin SCHEMBL2889815 | 0.92 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114714-A1 | SGK1 INHIBITORY COMPOSITIONS AND METHODS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-06-22 | — | — | WO | disclosed |