Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 17/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394855 | 0.90 | NT5E (0.49) | NT5EPRMT5WDR77 | |
| SCHEMBL21840060 | 0.83 | NT5E (0.55) | NT5E | |
| SCHEMBL30394758 | 0.78 | NT5E (0.67) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL30394629 | 0.75 | NT5E (0.40) | NT5EPRMT5WDR77 | |
| SCHEMBL30394412 | 0.75 | NT5E (0.41) | NT5EPRMT5WDR77 | |
| SCHEMBL30393370 | 0.74 | NT5E (0.44) | NT5EADORA3ADORA2AADORA1PRMT5 | |
| SCHEMBL23907442 | 0.74 | ADORA3 (0.50) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL21840012 | 0.74 | NT5E (0.53) | NT5E | |
| SCHEMBL23907552 | 0.73 | NT5E (0.47) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL30394929 | 0.73 | NT5E (0.57) | NT5EPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | PELOTON THERAPEUTICS INC. (US) | 2023-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | ENTPD5, ENTPD1, ENTPD3 | NT5E 5/4885ADORA3 9/4885ADORA2A 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.