Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 6/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395007 | 0.88 | KMT2A (0.79) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL27927962 | 0.88 | LMNA (0.81) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL3541913 | 0.87 | KMT2A (0.78) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL899489 | 0.87 | EPAS1 (0.77) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL10143953 | 0.84 | KMT2A (0.73) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL14096352 | 0.84 | ALDH1A1 (0.81) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL3553965 | 0.83 | TSHR (1.00) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL899061 | 0.82 | KMT2A (0.70) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL1225222 | 0.81 | LMNA (0.78) | EPAS1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL12694150 | 0.80 | ALDH1A1 (0.70) | EPAS1KMT2ALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116236478-A | Application of aromatic heterocyclic formamide compound | 浙江大学 | 2023-06-09 | — | — | CN | disclosed |