Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396959 | 0.87 | KDM4E (0.49) | ABCG2CYP1A2METAP2KDM4EFLT3 | |
| SCHEMBL28603472 | 0.87 | ULK1 (0.69) | ULK1ABCG2CYP1A2METAP2NOTUM | |
| SCHEMBL8198301 | 0.87 | KDM4E (0.47) | ABCG2GLAGAACYP1A2KMT2A | |
| SCHEMBL23148079 | 0.84 | NOTUM (0.46) | ULK1CYP1A2NOTUMKIF11IDO1 | |
| SCHEMBL30396363 | 0.83 | ULK1 (0.44) | ULK1CYP1A2NOTUMKIF11MAPK1 | |
| SCHEMBL2504301 | 0.81 | ULK1 (0.53) | ULK1GLAGAACYP1A2XDH | |
| SCHEMBL30310404 | 0.81 | ULK1 (0.53) | ULK1GLAGAACYP1A2XDH | |
| SCHEMBL6223883 | 0.80 | ULK1 (0.66) | ULK1ABCG2GLAGAACYP1A2 | |
| SCHEMBL8349745 | 0.78 | ULK1 (0.53) | ULK1GLAGAACYP1A2KMT2A | |
| SCHEMBL20494852 | 0.78 | ULK1 (0.53) | ULK1GLAGAACYP1A2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |