Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 3/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29007581 | 1.00 | MEN1 (0.47) | MEN1KMT2ACASP6GLASMN1; SMN2 | |
| SCHEMBL27601548 | 0.82 | MEN1 (0.44) | MEN1KMT2ACASP6GLASMN1; SMN2 | |
| SCHEMBL27897690 | 0.81 | PNMT (0.46) | MEN1KMT2ACASP6GLASMN1; SMN2 | |
| SCHEMBL29007602 | 0.80 | RAB9A (0.53) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30396872 | 0.79 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL9055148 | 0.79 | MAPT (0.52) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL29007598 | 0.76 | NR1H2 (0.50) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2673228 | 0.75 | SMN1; SMN2 (0.46) | MEN1KMT2AGLASMN1; SMN2MAPT | |
| SCHEMBL28010769 | 0.72 | GSK3B (0.59) | MAPTKDM4EHTTGAA | |
| SCHEMBL30429056 | 0.72 | HSD17B2 (0.41) | MEN1KMT2ACASP6GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209907-B | Method for synthesizing dihydrofuran containing 1, 3-indenodione spiro framework by utilizing microchannel reaction device | 南京先进生物材料与过程装备研究院有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116162076-B | Spirocyclic gamma-butyrolactone containing carboxylic acid tert-butyl ester and 1, 3-indene diketone structure and preparation method thereof | 南京工业大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-116162076-A | Spirocyclic gamma-butyrolactone containing carboxylic acid tert-butyl ester and 1, 3-indene diketone structure and preparation method thereof | 南京工业大学 | 2023-05-26 | — | — | CN | disclosed |