Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397944 | 0.82 | MAPK13 (0.41) | MAPK13GRM2TGFBR1 | |
| SCHEMBL25521381 | 0.80 | GRM2 (0.40) | MAPK13GRM2TNK2TNKS | |
| SCHEMBL30397971 | 0.80 | MAPK13 (0.36) | MAPK13GRM2 | |
| SCHEMBL30397831 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1 | |
| SCHEMBL25517516 | 0.75 | DRD2 (0.43) | MAPK13 | |
| SCHEMBL30397873 | 0.74 | MAPK14 (0.35) | TGFBR1 | |
| SCHEMBL30398426 | 0.73 | KDM5A (0.40) | ALDH1A1 | |
| SCHEMBL30397353 | 0.69 | CCR6 (0.44) | — | |
| SCHEMBL30397938 | 0.67 | MAPK13 (0.42) | MAPK13GRM2HRH3TGFBR1 | |
| SCHEMBL25526353 | 0.63 | GRM2 (0.43) | MAPK13GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |