Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | EIF4E | P06730 | 3/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962750 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL29461956 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL1558911 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL28302795 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL16581282 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL30397482 | 0.81 | TDP1 (0.58) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL2497892 | 0.81 | TDP1 (0.53) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL2501029 | 0.81 | TDP1 (0.58) | ALDH1A1TDP1EIF4EALDH3A1HIF1A | |
| SCHEMBL15055251 | 0.80 | ALDH1A1 (0.66) | ALDH1A1TDP1HIF1AMAPTADORA1 | |
| SCHEMBL2331432 | 0.80 | TDP1 (0.71) | ALDH1A1TDP1EIF4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500551-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2021-11-10 | — | — | EP | claimed |
| EP-3583093-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2021-04-14 | — | — | EP | claimed |
| US-10683256-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2020-06-16 | — | — | US | claimed |
| US-20190210954-A1 | Process for Preparing Substituted Biphenyls | LIANHE CHEMICAL TECHNOLOGY CO., LTD (CN) | 2019-07-11 | — | — | US | claimed |
| WO-2018149813-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2018-08-23 | — | — | WO | claimed |
| EP-2303828-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2014-07-30 | — | — | EP | claimed |
| US-20110105766-A1 | Method for Producing Substituted Biphenyls | BASF SE (DE) | 2011-05-05 | — | — | US | claimed |
| EP-2303828-A2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2011-04-06 | — | — | EP | claimed |
| WO-2009156359-A2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-12-30 | — | — | WO | claimed |
| US-20240270677-A1 | Process for Preparing Substituted Biphenyls via Suzuki Coupling of Aryl-Chlorides | BASF SE (DE) | 2024-08-15 | — | — | US | disclosed |
| EP-4341239-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS VIA SUZUKI COUPLING OF ARYL-CHLORIDES | BASF SE (DE) | 2024-03-27 | — | — | EP | disclosed |
| CN-117088777-A | Method for preparing 2-nitrobiphenyl compound | 南通泰禾化工股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117088776-A | Method for preparing 2-nitrobiphenyl compound | 江西天宇化工有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116253646-A | Synthesis method and application of 2-nitro-1, 1' -biphenyl compound | 湖南海利化工股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-2303828-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2700630-A2 | Method for producing substituted biphenyls | BASF SE (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-8461390-B2 | Method for producing substituted biphenyls | BASF SE (DE) | 2013-06-11 | — | — | US | disclosed |
| US-20110105766-A1 | Method for Producing Substituted Biphenyls | BASF SE (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2303828-A2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009156359-A2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683256-B2 | Process for preparing substituted biphenyls | PIK3CA, PIK3CB, PIK3CG | ALDH1A1 3096/4885TDP1 3114/4885EIF4E 2662/4885 |
| US-20190210954-A1 | Process for Preparing Substituted Biphenyls | PIK3CA, PIK3CB, PIK3CG | ALDH1A1 3096/4885TDP1 3114/4885EIF4E 2662/4885 |
| US-20110105766-A1 | Method for Producing Substituted Biphenyls | C5, CTRB1, CFB | ALDH1A1 2105/4885TDP1 2267/4885EIF4E 3500/4885 |
| US-20240270677-A1 | Process for Preparing Substituted Biphenyls via Suzuki Coupling of Aryl-Chlorides | CYP2B6, DDT, CYP1B1 | ALDH1A1 517/4885TDP1 3771/4885EIF4E 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.