Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25525059 | 0.88 | BTK (0.41) | BTKRETJAK3KMT2AL3MBTL1 | |
| SCHEMBL25525043 | 0.87 | SUV39H2 (0.44) | BTKRETJAK3KMT2AL3MBTL1 | |
| SCHEMBL30397473 | 0.86 | BTK (0.40) | BTKKMT2AL3MBTL1SUV39H2KDM4D | |
| SCHEMBL25517516 | 0.81 | DRD2 (0.43) | BTKJAK3KMT2AL3MBTL1SUV39H2 | |
| SCHEMBL25522632 | 0.80 | MAPK13 (0.42) | BTKKMT2AL3MBTL1 | |
| SCHEMBL25525729 | 0.79 | BTK (0.43) | BTKKMT2AL3MBTL1SUV39H2KDM4D | |
| SCHEMBL25540956 | 0.79 | BTK (0.42) | BTKKMT2AL3MBTL1 | |
| SCHEMBL25525052 | 0.77 | BTK (0.43) | BTKJAK3KMT2AL3MBTL1SUV39H2 | |
| SCHEMBL25533067 | 0.77 | BTK (0.44) | BTKJAK3KMT2AL3MBTL1JAK2 | |
| SCHEMBL25523570 | 0.77 | BTK (0.44) | BTKJAK3KMT2AL3MBTL1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |