Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.52 |
| ▸ | FEN1 | P39748 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GCK | P35557 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062548 | 1.00 | POLB (0.53) | POLBKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL13788913 | 0.84 | KMT2A (0.63) | POLBKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL13206961 | 0.84 | L3MBTL1 (0.51) | POLBKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL5342056 | 0.84 | TSHR (0.71) | KMT2AMEN1GAAALOX5APFEN1 | |
| SCHEMBL8140330 | 0.82 | TSHR (0.75) | KMT2AMEN1GAAL3MBTL1ALOX5AP | |
| SCHEMBL1439966 | 0.82 | TSHR (0.75) | KMT2AMEN1GAAL3MBTL1ALOX5AP | |
| SCHEMBL3247291 | 0.81 | CNR1 (0.56) | POLBKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL10037158 | 0.79 | USP2 (0.51) | KMT2AMEN1GAAALOX5APFEN1 | |
| SCHEMBL3343329 | 0.79 | PKM (0.58) | POLBKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL20627051 | 0.79 | POLB (0.53) | POLBKMT2AMEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4716529-A2 | COMPOUNDS THAT RE-ACTIVATE MUTANT P53 | Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (US) | 2026-04-01 | — | — | EP | disclosed |
| WO-2024243343-A2 | COMPOUNDS THAT RE-ACTIVATE MUTANT P53 | KARANICOLAS JOHN (US) | 2024-11-28 | — | — | WO | disclosed |
| CN-116059196-A | Compounds and methods for inducing cartilage formation | 斯克利普斯研究所 | 2023-05-05 | — | — | CN | disclosed |