Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023181 | 0.87 | CCR2 (0.45) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3039474 | 0.86 | CCR2 (0.44) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3043761 | 0.85 | CCR2 (0.45) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3029490 | 0.85 | NPSR1 (0.49) | CCR2KCNH2CYP2D6TSHR | |
| SCHEMBL3033045 | 0.85 | CCR2 (0.44) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3029680 | 0.84 | CCR2 (0.44) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3029508 | 0.83 | CCR2 (0.44) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3034424 | 0.83 | CCR2 (0.43) | CCR2KCNH2CYP2D6TSHR | |
| SCHEMBL3038733 | 0.83 | KCNH2 (0.47) | CCR2KCNH2CYP3A4CYP2D6TSHR | |
| SCHEMBL3041684 | 0.82 | CCR2 (0.47) | CCR2KCNH2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | claimed |
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | CCR2, CCR1, CCR5 | CCR2 1/4885KCNH2 4417/4885CYP3A4 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.