Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | ABL2 | P42684 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25150828 | 1.00 | USP30 (0.42) | USP30SRCEGFRABL1ABL2 | |
| SCHEMBL30186818 | 0.94 | DPP4 (0.42) | USP30FPR2DPP4TRPV3TP53 | |
| SCHEMBL25151191 | 0.94 | DPP4 (0.42) | USP30FPR2DPP4TRPV3TP53 | |
| SCHEMBL25151962 | 0.88 | PDE4B (0.43) | USP30SRCEGFRABL1ABL2 | |
| SCHEMBL30399707 | 0.88 | PDE4B (0.43) | USP30SRCEGFRABL1ABL2 | |
| SCHEMBL25150803 | 0.83 | FPR2 (0.33) | USP30FPR2DPP4TRPV3TP53 | |
| SCHEMBL25151052 | 0.82 | STS (0.43) | USP30FPR2TP53 | |
| SCHEMBL16764188 | 0.82 | HRH3 (0.43) | USP30SRCEGFRFPR2TRPV3 | |
| SCHEMBL16764187 | 0.82 | HRH3 (0.43) | USP30SRCEGFRFPR2TRPV3 | |
| SCHEMBL25150890 | 0.82 | HCAR1 (0.45) | USP30SRCEGFRABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416141-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | Remix Therapeutics Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |